{"id":2013,"date":"2026-03-10T05:47:45","date_gmt":"2026-03-10T05:47:45","guid":{"rendered":"https:\/\/owspakistan.com\/?p=2013"},"modified":"2026-03-10T05:47:45","modified_gmt":"2026-03-10T05:47:45","slug":"d41586-026-00741-3","status":"publish","type":"post","link":"https:\/\/owspakistan.com\/?p=2013","title":{"rendered":"Daily multivitamin slows signs of biological ageing"},"content":{"rendered":"<div data-test=\"access-teaser\">\n<figure class=\"figure\"><picture class=\"embed intensity--high\"><source type=\"image\/webp\" srcset=\"https:\/\/media.nature.com\/lw767\/magazine-assets\/d41586-026-00741-3\/d41586-026-00741-3_52157840.jpg?as=webp 767w, https:\/\/media.nature.com\/lw319\/magazine-assets\/d41586-026-00741-3\/d41586-026-00741-3_52157840.jpg?as=webp 319w\" sizes=\"(max-width: 319px) 319px, (min-width: 1023px) 100vw,  767px\"\/><img decoding=\"async\" class=\"figure__image\" alt=\"A senior woman in a swimsuit and swimming cap laughs while enjoying a wild swim in a large outdoor lake.\" loading=\"lazy\" src=\"https:\/\/media.nature.com\/lw767\/magazine-assets\/d41586-026-00741-3\/d41586-026-00741-3_52157840.jpg\"\/><figcaption>\n<p class=\"figure__caption u-sans-serif\"><span class=\"mr10\">Taking multivitamins daily was associated with changes in epigenetic ageing \u2018clocks\u2019.<\/span><span>Credit: Halfpoint Images\/Getty<\/span><\/p>\n<\/figcaption><\/picture><\/figure>\n<p>Taking a multivitamin every day can slow certain markers of biological ageing, a new study suggests.<\/p>\n<p>The research, published in <i>Nature Medicine <\/i>on 9 March<sup><a href=\"#ref-CR1\" data-track=\"click\" data-action=\"anchor-link\" data-track-label=\"go to reference\" data-track-category=\"references\">1<\/a><\/sup>, reveals that taking a daily supplement for two years slowed biological ageing in older adults by around four months, compared with those who didn\u2019t take them.<\/p>\n<p>The effect was more pronounced in people who already showed signs of accelerated <a href=\"https:\/\/www.nature.com\/articles\/d41586-021-01915-x\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-021-01915-x\" data-track-category=\"body text link\" target=\"_blank\" rel=\"noopener\">biological ageing<\/a>, meaning that their calculated biological age was greater than their chronological age.<\/p>\n<p>The aim of studies like this is \u201cnot just identifying how to live longer, but also how to live better\u201d, says study co-author Howard Sesso, an epidemiologist at Brigham and Women\u2019s Hospital in Boston, Massachusetts. Although it\u2019s too early to link the data to clinical outcomes, \u201cthe multivitamin intervention appeared to be on that type of trajectory over two years,\u201d he says.<\/p>\n<p><article class=\"recommended pull pull--left u-sans-serif\" data-label=\"Related\"><a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00879-6\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/media.nature.com\/w400\/magazine-assets\/d41586-026-00741-3\/d41586-026-00741-3_51310604.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">The best foods for healthy ageing \u2015 and the worst<\/p>\n<p><\/a><\/article>\n<\/p>\n<p>\u201cThis is a very interesting and rigorous study,\u201d says Steve Horvath, a geroscientist at biotechnology company Altos Labs in Cambridge, UK. \u201cThe public appetite for knowing whether everyday supplements can genuinely slow ageing is enormous. This study provides some of the most credible evidence we have to date.\u201d<\/p>\n<h2>Slowing down the clock<\/h2>\n<p>Sesso and his colleagues analysed blood samples from 958 healthy participants in the COSMOS study, a randomized controlled trial in the United States, who were 70 years old on average. The samples were taken at three time points: when they enrolled in the study and after 12 and 24 months.<\/p>\n<p>To calculate people\u2019s biological ages at the time of each sample, the team analysed five epigenetic \u2018clocks\u2019 in the blood samples. These clocks are biomarkers that measure DNA methylation \u2014 patterns of molecular tags on DNA \u2014 at specific sites in the genome. Methylation levels increase or decrease at particular sites in a relatively<a href=\"https:\/\/www.nature.com\/articles\/d41586-020-03119-1\" data-track=\"click\" data-label=\"https:\/\/www.nature.com\/articles\/d41586-020-03119-1\" data-track-category=\"body text link\" target=\"_blank\" rel=\"noopener\"> predictable manner with age<\/a>.<\/p>\n<p>The researchers found that taking a daily multivitamin significantly slowed markers of ageing in two of the five clocks \u2014 both of which can be used to indicate mortality risk.<\/p>\n<p>The beneficial effect of daily multivitamins on biological ageing markers is small, but \u201cthis kind of consistency across different epigenetic clocks is exactly what you want to see\u201d, says Horvath, who developed one of the clocks used.<\/p>\n<p><article class=\"recommended pull pull--left u-sans-serif\" data-label=\"Related\"><a href=\"https:\/\/www.nature.com\/articles\/d41586-025-00355-1\" class=\"u-link-inherit\" data-track=\"click\" data-track-label=\"recommended article\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" class=\"recommended__image\" alt=\"\" src=\"https:\/\/media.nature.com\/w400\/magazine-assets\/d41586-026-00741-3\/d41586-026-00741-3_50670694.jpg\"\/><\/p>\n<p class=\"recommended__title u-serif\">Omega-3 supplements slow biological ageing<\/p>\n<p><\/a><\/article>\n<\/p>\n<\/div>\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Taking multivitamins daily was associated with changes in epigenetic ageing \u2018clocks\u2019.Credit: Halfpoint Images\/Getty Taking a multivitamin every day can slow certain markers of biological ageing, a new study suggests. The research, published in Nature Medicine on 9 March1, reveals that taking a daily supplement for two years slowed biological ageing in older adults by around<\/p>\n","protected":false},"author":1,"featured_media":2014,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[569,570,98,99,571,97],"class_list":["post-2013","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-ageing","tag-epigenetics","tag-humanities-and-social-sciences","tag-multidisciplinary","tag-nutrition","tag-science"],"jetpack_publicize_connections":[],"_links":{"self":[{"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/posts\/2013","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/owspakistan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2013"}],"version-history":[{"count":0,"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/posts\/2013\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/owspakistan.com\/index.php?rest_route=\/wp\/v2\/media\/2014"}],"wp:attachment":[{"href":"https:\/\/owspakistan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2013"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/owspakistan.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2013"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/owspakistan.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2013"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}