Companies use western blots in their catalogues to provide confirmation that their antibodies work as they are supposed to. Credit: Manjurul/Getty Thousands of antibodies sold by multiple research vendors have images associated with their catalogue entries that seem to have been digitally altered, according to a scientific-integrity specialist. The finding comes after more than 100
The β-galactosidase molecule can be targeted by antibodies in experiments. But some studies have erroneously used the antibody that targets the bacterial β-galactosidase instead of the mammalian version.Credit: Laguna Design/Science Photo Library More than 50 studies on cell ageing have apparently used the wrong antibody to identify a key protein in experiments, according to a