Animal studies and cryosectioning C57BL/6J adult mice (8 weeks old or 12 weeks old in pregnancy-related studies) were used in this study. Mice were group-housed in the École Polytechnique Fédérale de Lausanne (EPFL) animal facility on 12-h light/dark cycles, at ambient temperature and humidity, with ad libitum access to food and water; pregnant female mice were maintained group-housed
All surgical and experimental procedures were in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals and approved by the Animal Care and Use Committees of the Allen Institute or Johns Hopkins University. Allocations of mice to experiments were randomized and experimenter blind. Mice were housed at 20–22 °C
Ethics statement All experiments involving human cell lines were approved by the Harvard University IRB and ESCRO committees. All animal experiments were conducted according to protocols approved by the Institutional Animal Care and Use Committee (IACUC) of Harvard University. All experiments were performed in accordance with relevant guidelines and regulations, and in accordance with informed
Mouse models All animal experiments at the University of California Los Angeles (UCLA) were conducted in accordance with the US National Institutes of Health (NIH) Guide for the Care and Use of Laboratory Animals and were approved by the Chancellor’s Animal Research Committee at UCLA. The UCLA ARC protocol numbers for the experiments were 2009-043, 2020-002, 2017-039
