A bacterial enzyme that indiscriminately cuts DNA (artist’s illustration) has been harnessed to kill cancer cells. Credit: KTSDesign/Scientific Photo Library Scientists have exploited a peculiar CRISPR enzyme to fight cancer by shredding the DNA of cancer cells, causing them to self-destruct. The enzyme can be programmed to recognize a specific messenger RNA, such as that
An enzyme cuts DNA (artist’s impression). Synthetic enzymes that cleave proteins were rapidly designed with the help of artificial intelligence.Credit: Artur Plawgo/Scientific Photo Library Scientists have leveraged artificial intelligence models to create synthetic CRISPR proteins that edit the genome more efficiently than their natural counterparts. These synthetic CRISPR systems could one day drive discoveries in