Department of Psychology, Michigan State University, East Lansing, MI, USA Ted Schwaba, Lindsay S. Ackerman & Josephine C. M. Fealy Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, United States Margaret L. Clapp Sullivan Department of Biological Psychology, Faculty of Behavioural and Movement Sciences, Vrije Universiteit, Amsterdam, The Netherlands Wonuola A. Akingbuwa, Eco J. C. de
Pangenome reference The pangenome reference used in this study is a sequence graph augmented with phased small variants. It is stored in two data files: a sequence graph in reference rGFA format16 containing the structural variants and a supplementary phased VCF33 file containing small variants. The rGFA sequence graph is constructed first from haplotype assemblies,
Study population The genetic discovery analysis of TG:HDL ratio encompassed multiple cohorts with a cumulative sample size of 1,032,116 participants. Study participants were recruited from various population-based and hospital-based health systems across three continents (Fig. 1 and Supplementary Table 1). These cohorts included: the UK Biobank population-based study (UKB, n = 409,602)60; the Geisinger Health System MyCode
