Metabolism Archives - OWS Pakistan

Switching off the FNIP1 gene protects against metabolic disease 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- August 8, 2026
RESEARCH BRIEFINGS 05 August 2026 A study of more than one million people shows that rare genetic variants that disrupt the FNIP1 gene are associated with a favourable metabolic profile and a roughly 60% lower risk of cardiometabolic disease than the general population. Silencing genes in the FNIP1 pathway in mice induces fat breakdown and
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More muscle, less belly fat: mutations to a gene are linked to wide-ranging benefits 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- August 8, 2026
The ratio of fat tissue (fat droplets in yellow; artificially coloured) to muscle mass is reduced in people with newly identified variants of a gene that affects cellular metabolism. Credit: Steve Gschmeissner/Science Photo Library A massive genomic study has linked mutations in a specific gene to an increased proportion of muscle, decreased levels of belly
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FNIP1 variants are associated with favourable metabolism in 1 million humans – Nature 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- August 8, 2026
Study population The genetic discovery analysis of TG:HDL ratio encompassed multiple cohorts with a cumulative sample size of 1,032,116 participants. Study participants were recruited from various population-based and hospital-based health systems across three continents (Fig. 1 and Supplementary Table 1). These cohorts included: the UK Biobank population-based study (UKB, n = 409,602)60; the Geisinger Health System MyCode
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An ancient mitochondrial program tunes translation to haem availability – Nature 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- August 6, 2026
Cell lines and culture HAP1 cells were cultured in Iscove’s modified Dulbecco’s medium (IMDM) (Thermo Fisher Scientific) supplemented with 10% heat-inactivated fetal calf serum (FCS) (BioSell) and 1% penicillin–streptomycin–glutamine (PSG) solution (Thermo Fisher Scientific). 293T (HEK293T), A549, HeLa, U2OS, BJEH and HCT116 cells were maintained in Dulbecco’s modified Eagle’s medium (DMEM) (Thermo Fisher Scientific) supplemented
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The breathalyzer can detect if you are burning fat with a single exhale 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- July 23, 2026
Molecules released in the breath can indicate whether the body is burning fat.Credit: Pet/Getty A portable breath test can accurately measure when the body burns fat in real time1. The device could be used by people trying to monitor weight loss without having to wait weeks to see a change on the scale, although researchers
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Why do astronauts’ bodies wear out? Space Station study points to mitochondria 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- July 16, 2026
Mitochondria (green in this false-color transmission electron micrograph) may play a role in the physiological effects of microgravity.Credit: José Calvo/Scientific Photography Library Researchers have found that exposure to microgravity aboard the International Space Station causes mitochondria in human cells and worms to produce fewer proteins. The work also identified a previously unknown molecular pathway that
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