Animal studies and cryosectioning C57BL/6J adult mice (8 weeks old or 12 weeks old in pregnancy-related studies) were used in this study. Mice were group-housed in the École Polytechnique Fédérale de Lausanne (EPFL) animal facility on 12-h light/dark cycles, at ambient temperature and humidity, with ad libitum access to food and water; pregnant female mice were maintained group-housed
Human tissue and ethical approval Post-mortem human brain specimens were obtained from the Department of Neuroscience at Yale University School of Medicine, the Birth Defects Research Laboratory at the University of Washington, Advanced Bioscience Resources (ABR), the Human Brain Collection Core (HBCC), the Brain and Tissue Bank at the University of Maryland, the MRC–Wellcome Trust
Mouse models All animal experiments at the University of California Los Angeles (UCLA) were conducted in accordance with the US National Institutes of Health (NIH) Guide for the Care and Use of Laboratory Animals and were approved by the Chancellor’s Animal Research Committee at UCLA. The UCLA ARC protocol numbers for the experiments were 2009-043, 2020-002, 2017-039
