Mice All mouse handling and maintenance was performed according to the regulations of the Institutional Animal Care and Use Committee of the Albert Einstein College of Medicine (protocol 00001393). Sstflp+/+; Nos1creER+/− and Sstflp+/−;Nos1creER+/− mice were used interchangeably in this study, with no differences detected between the two groups (Nos1creER, Jax 014541; Sstflp, Jax 031629). Nos1creER+/−
Mice All mouse experiments were performed according to protocols approved by the Institutional Animal Care and Use Committees (IACUC) at Korea Advanced Institute of Science and Technology (KAIST) and the Institute for Basic Science (IBS), adhering strictly to ethical guidelines. B6.Cg-Tg(APPswe, PSEN1dE9)85Dbo/Mmjax (APP/PS1) mice and B6.Cg-Tg(APPSwFlLon, PSEN1*M146L*L286V)6799Vas/Mmjax (5×FAD) mice were produced in our laboratory and
Lee, H. G., Lee, J. H., Flausino, L. E. & Quintana, F. J. Neuroinflammation: an astrocyte perspective. Sci. Transl. Med. 15, eadi7828 (2023). Article CAS PubMed Google Scholar Clark, I. C. et al. Barcoded viral tracing of single-cell interactions in central nervous system inflammation. Science 372, eabf1230 (2021). Article CAS PubMed PubMed Central Google Scholar
Early-career scientists in China face intense competition for entry-level jobs. Credit: Xinhua/Shutterstock China’s top research funding agency will increase the number of prestigious grants for early-career scientists by 50%. The move is part of the country’s pledge to increase support for young scientists, who face intense competition to secure funding and jobs. Early career researchers