RESEARCH BRIEFINGS 05 August 2026 A study of more than one million people shows that rare genetic variants that disrupt the FNIP1 gene are associated with a favourable metabolic profile and a roughly 60% lower risk of cardiometabolic disease than the general population. Silencing genes in the FNIP1 pathway in mice induces fat breakdown and
One set of neurons helps the heart (pictured, a mouse’s heart) keep beating steadily, and another set buffers the heartbeat against acute stress.Credit: Steve Gschmeissner/SPL Each heartbeat is choreographed not only by the brain but also by a mysterious nervous system embedded in the heart itself. Now, scientists studying mice have begun to unravel how
