Carnevale, J. et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609, 174–182 (2022). Article ADS CAS PubMed PubMed Central Google Scholar Freitas, K. A. et al. Enhanced T cell effector activity by targeting the Mediator kinase module. Science 378, eabn5647 (2022). Article CAS PubMed PubMed Central Google Scholar Brudno,
Bispecific antibodies (orange and yellow, artist’s illustration) grab onto two different proteins rather than the standard one.Credit: Thom Leach/Science Photo Library Cancer-fighting drugs called bispecific antibodies are having a moment. A growing number are making their way into the clinic, and researchers are developing increasingly elaborate molecules with new capabilities. In the past five years,