Mice C57BL/6, P14 TCR-transgenic (Tg)45, pmel TCR-Tg46 and Rosa26-Cas9 knock-in47 mice were purchased from the Jackson Laboratory. Human CD19 CAR-Tg mice were provided by T. Geiger36. We crossed Rosa26-Cas9 knock-in mice with P14, pmel or human CD19 (hCD19) CAR-Tg mice to express Cas9 in antigen-specific CD8+ T cells. The Cas9-expressing mice were fully backcrossed to
Premiering out of Venice Immersive, “Nevatars” has long been a passion project for director Andy Serkis. It took root when Serkis and partner Jonathan Cavendish co-founded The Imaginarium, a production studio built on Serkis’ deep expertise in performance capture. They had the hardware, the knowledge — and, it turns out, had been sitting on the
A wave of overnight Russian missile strikes has killed at least eight people in the capital Kyiv and the surrounding region, Ukrainian authorities say. Apartment blocks, warehouses, a children’s hospital and a school were hit in the “massive attack” on Thursday, according to the State Emergency Service of Ukraine (DSNS). At least least 33 people
