Explanation: This sight was worth getting out of bed early. Just over four years ago, Comet C/2020 F3 (NEOWISE) rose before dawn to the delight of northern sky enthusiasts awake that early. Up before sunrise on July 8th, the featured photographer was able to capture in dramatic fashion one of the few comets visible to the unaided eye this century, an inner-Solar
PPCG cohort, WGS and variant calling We used data from the PPCG consortium of primary prostate cancer samples from a total of 1,001 prostate cancer donors with 1,172 tumour samples. Informed ethical consent was obtained at clinical follow-up, and was consistent with local research ethics and International Cancer Genome Consortium (ICGC) guidelines (https://icgc.org/). Ethical approval
Sattler, J. J. H. B., Ruiz-Martinez, J., Santillan-Jimenez, E. & Weckhuysen, B. M. Catalytic dehydrogenation of light alkanes on metals and metal oxides. Chem. Rev. 114, 10613–10653 (2014). Article CAS PubMed Google Scholar Gunanathan, C. & Milstein, D. Applications of acceptorless dehydrogenation and related transformations in chemical synthesis. Science 341, 1229712 (2013). Article ADS PubMed
Schneider, J. L., Lin, J. J. & Shaw, A. T. ALK-positive lung cancer: a moving target. Nat Cancer 4, 330–343 (2023). Article CAS PubMed PubMed Central Google Scholar Voena, C., Ambrogio, C., Iannelli, F. & Chiarle, R. ALK in cancer: from function to therapeutic targeting. Nat. Rev. Cancer 25, 359–378 (2025). Article CAS PubMed PubMed
Experimental model and subject details Zebrafish husbandry Zebrafish were reared at 28.5 °C in 14–10-h light–dark cycles (conductivity of 1,000 μS, adjusted via Instant Ocean Sea Salt (approximately 30 g l−1), pH 7.0, adjusted using sodium bicarbonate)69. Zebrafish from 5 to 14 days post-fertilization were fed rotifers and used for experiments. All experiments complied with protocols approved by the
Benegas, G., Ye, C., Albors, C., Li, J. C. & Song, Y. S. Genomic language models: opportunities and challenges. Trends Genet. 41, 286–302 (2025). Article CAS PubMed Google Scholar Benegas, G., Eraslan, G. & Song, Y. S. Benchmarking DNA sequence models for causal regulatory variant prediction in human genetics. Preprint at bioRxiv https://doi.org/10.1101/2025.02.11.637758 (2025). Dalla-Torre,