Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. Credit: Jessie C. Tanner Female Cope’s gray treefrogs (Dryophytes chrysoscelis) struggle to pick the best mates when presented with too much choice. Typically, female treefrogs choose male suitors with the longest calls. When researchers played these
People who live to 110 years and older have large populations of a rare type of immune cell that can kill cancer1, finds a study published today in Cell Reports. It is possible that such cells, called killer T cells, might help people to live to extraordinarily long ages by fighting off cancer — although
Carnevale, J. et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609, 174–182 (2022). Article ADS CAS PubMed PubMed Central Google Scholar Freitas, K. A. et al. Enhanced T cell effector activity by targeting the Mediator kinase module. Science 378, eabn5647 (2022). Article CAS PubMed PubMed Central Google Scholar Brudno,
There was desperation in the voice of the young Ethiopian man when he managed to get through to the BBC from a phone in his prison cell on death row in Saudi Arabia. Habtom, whose name – like the other prisoner featured in this article – has been changed to protect his identity, has been
A bacterial enzyme that indiscriminately cuts DNA (artist’s illustration) has been harnessed to kill cancer cells. Credit: KTSDesign/Scientific Photo Library Scientists have exploited a peculiar CRISPR enzyme to fight cancer by shredding the DNA of cancer cells, causing them to self-destruct. The enzyme can be programmed to recognize a specific messenger RNA, such as that
Albelda, SM CAR T cell therapy for patients with solid tumors: key lessons to learn and unlearn. Nat. Rev. Clin. Oncol. 2147–66 (2024). Article PubMed Google Scholar Fu, Q. et al. RUNX-3-expressing CAR T cells targeting glypican-3 in patients with heavily pretreated advanced hepatocellular carcinoma: a phase I trial. ECclinicalMedicine 63102175 (2023). Article PubMed PubMed
