The method called prime editing can make fine-scale edits to DNA (artist’s illustration).Credit: Patrick Landmann/Science Photo Library A powerful gene-editing technique has been used to edit DNA directly in a person’s body — the first known instance of such a treatment. The milestone treatment is part of a clinical trial of prime editing, a technique
Conventional cereals and grains could be grown alongside gene-edited crops under amended EU rules.Credit: Joe Klamar/AFP via Getty In June, the European Union overturned its strict limits on the cultivation of gene-edited crops. The change comes in the wake of growing criticism that Europe lags behind other regions when it comes to adopting innovative plant
Carnevale, J. et al. RASA2 ablation in T cells boosts antigen sensitivity and long-term function. Nature 609, 174–182 (2022). Article ADS CAS PubMed PubMed Central Google Scholar Freitas, K. A. et al. Enhanced T cell effector activity by targeting the Mediator kinase module. Science 378, eabn5647 (2022). Article CAS PubMed PubMed Central Google Scholar Brudno,
A bacterial enzyme that indiscriminately cuts DNA (artist’s illustration) has been harnessed to kill cancer cells. Credit: KTSDesign/Scientific Photo Library Scientists have exploited a peculiar CRISPR enzyme to fight cancer by shredding the DNA of cancer cells, causing them to self-destruct. The enzyme can be programmed to recognize a specific messenger RNA, such as that
You have full access to this article through your institution. Hello Nature Readers, would you like to receive this report in your inbox for free every day? Register here. This dagger was buried next to Ita, a daughter of Pharaoh Amenemhat II, who “was a young woman between 28 and 34 years old with strong
An enzyme cuts DNA (artist’s impression). Synthetic enzymes that cleave proteins were rapidly designed with the help of artificial intelligence.Credit: Artur Plawgo/Scientific Photo Library Scientists have leveraged artificial intelligence models to create synthetic CRISPR proteins that edit the genome more efficiently than their natural counterparts. These synthetic CRISPR systems could one day drive discoveries in
