Houses are partially submerged in muddy water following flash floods in Nepal.Credit: Prabin RANABHAT/AFP via Getty Around 350 people have died and more than 1,000 are missing, after a deadly deluge of rocks, mud and water hit villages along the border of Nepal and Tibet on Wednesday. The US Geological Survey says the event was
The Nancy Grace Roman Space Telescope undergoes vibration testing before its launch, scheduled for 30 August. Credit: Sydney Rohde/NASA/Roman Space Telescope (CC BY-NC-ND 4.0) It’s crunch time at NASA’s Goddard Space Flight Center. Since earlier this summer, a countdown clock by the campus’s main gate in Greenbelt, Maryland, has been ticking down to 30 August.
When I began my research career nearly a decade ago, there were no female academics in the mining-engineering department at Central South University in Changsha, China. Only this year did the department appoint me as its first female professor. I welcome that change, but it shows that the expectations around who can pursue mining careers
Fauci, A. S. & Folkers, G. K. Pandemic preparedness and response: lessons from COVID-19. J. Infect. Dis. 228, 422–425 (2023). Article PubMed Google Scholar Rappuoli, R., Alter, G. & Pulendran, B. Transforming vaccinology. Cell 187, 5171–5194 (2024). Article CAS PubMed PubMed Central Google Scholar Pulendran, B., Li, S. & Nakaya, H. I. Systems vaccinology. Immunity
CIGMA We developed CIGMA to unbiasedly quantify cell-type-shared and cell-type-specific eQTLs in scRNA-seq data. CIGMA avoids bias from eQTL detection power by using a linear mixed model, similar to the GREML model of complex trait heritability12. CIGMA models cell-type-specific pseudobulk data, which is computed by averaging across all cells in predefined cell types, one gene
The Malva platform Malva provides a unified interface to search millions of cells by any RNA sequence. Malva integrates five modular components that operate independently but communicate through a central orchestrator (Extended Data Fig. 1b). When a user submits a query via the public RESTful API—a gene symbol, DNA sequence, or natural language request such