The method called prime editing can make fine-scale edits to DNA (artist’s illustration).Credit: Patrick Landmann/Science Photo Library A powerful gene-editing technique has been used to edit DNA directly in a person’s body — the first known instance of such a treatment. The milestone treatment is part of a clinical trial of prime editing, a technique
A new species of sea spider, Tanystylum kiixin, has been discovered.Credit: Cormac Toler-Scott Amid wars, AI doom and a super El Niño, good news can seem in short supply. But it is there if you go looking. In Nature’s latest collection of stories selected to bring readers joy, learn about a country that has reversed
Regenerative medicine holds extraordinary promise for transforming the treatment of chronic and life-threatening diseases. Yet the field continues to advance on an incomplete scientific foundation: the underrepresentation of women and non-binary people in both preclinical and clinical research. This is not a minor oversight, but a fundamental limitation that compromises the safety, accuracy and translational
Hongkui Deng, who has been working on a trial involving iPSC transplants, is observed by students. By the age of 25, Mingyu, a pseudonym being used to protect her privacy, had already undergone two liver transplants and a pancreas transplant in an effort to treat her type 1 diabetes. In her ten years living with
Some people taking the new generation of obesity drugs lose one-quarter of their body weight.Credit: Peter Dazeley/Getty Most people taking the popular GLP-1 drugs shed substantial amounts of weight — an average of one-quarter of their body weight according to one study1. So why do 10–15% of people using the drugs lose minimal weight or
This ingestible capsule, tested in pigs, contains a biodegradable paper battery (large brown circular structure) and a radio-frequency identification (RFID) tag (black lines).Credit: Mehmet Say A battery made with a substance resembling edible rice paper can power swallowable electronic medical devices. And after the battery has been safely digested, its broken-down ingredients can be absorbed
