Automated prototyping of genetic codes – Nature0

• SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
• August 29, 2026

tRNA in vitro production Oligonucleotides containing tRNA under a T7 promoter and followed by an HDV ribozyme61 were synthesized by IDT as high-fidelity DNA microchip oligo pools from 254–275 nucleotides in length, and dsDNA was amplified in a single PCR reaction for each pool. These tRNA pools included 48 unique E. coli isoacceptor tRNAs with