Science Mission Directorate Archives - Page 2 of 138

Molecular-level observation of the self-assembly of a virus-like particle – Nature 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Expression and purification of SC003-mi3 VLP The mi3-VLP (also known as SC003-mi3) was derived from i3-01 (ref. 66) by introducing two mutations that remove surface-exposed cysteines to prevent aggregation and by genetically fusing a SpyCatcher domain to the N-terminus to enable plug-and-play attachment of SpyTagged proteins54. The plasmid pET28a-SpyCatcher003(SC003)-mi3 (gift from Professor Mark Howarth, Cambridge University)
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Developmental xenocortication using human-derived organoids in mice – Nature 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Genetically encoded cortical depletion Emx1-cre (JAX, B6.129S2-Emx1tm1(cre)Krj/J), Esco2fl/fl (JAX, B6N.129S-Esco2tm1.1Ge/J) and C57BL SCID (JAX, B6.Cg-Prkdcscid/SzJ) mice were used to generate the breeding scheme: male Esco2fl/flPrkdcscid/scid × female Emx1-cre+/−Esco2fl/+Prkdcscid/scid. Breeder and offspring cages were supplemented with breeder chow (Envigo Teklad 2919) and DietGel 76A (with plant protein) to help to increase pup survival. Some breeders were more prone to
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Development of a random background to understand ligand optimization – Nature 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
ChEMBL database molecular pairs From the PostgreSQL version of CHEMBL34 (ref. 4) (https://doi.org/10.6019/CHEMBL.database.34), we filtered the database for compounds with activities reported against a single protein, with either Ki, Kd, IC50 or EC50 as the activity type. To be considered a molecular pair, compounds had to have the same assay ID, the same target ID,
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Is it safe to use consumer wearable devices for research?0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Wuyou Sui, a researcher at Western University in London, Canada, explains some of the ethical considerations of using digital wearable technology in research.Credit: Anna Sui Consumer wearables, such as smart watches or rings, can help people to track their daily steps, heart rate and sleep patterns. Given the devices’ popularity and ease of use, researchers
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Will wearable technologies transform clinical trials?0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Digital wearables are currently used to monitor glucose, but could potentially be used to measure substances such as glutamate and cortisol.Credit: Halfpoint Images/Getty The year is 2036. Researchers conducting a randomized clinical trial issue 200 volunteers with wearable devices to capture metrics on their heart rate, blood pressure, hormone levels and activity. Doses of a
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AI tool turns any paper into an ‘agent’ that can collaborate and answer complex queries 0
- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
AI agents representing papers could foster cross-disciplinary collaboration. Credit: Getty A new artificial-intelligence tool quickly transforms a research paper into a bespoke AI agent that serves as a “virtual corresponding author”. The agent can respond immediately to questions about the paper, providing a convenient way for scientists to grasp advances in unfamiliar fields. It can
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