Artificial intelligence is reshaping the world in front of our eyes. The concerns around AI, however, extend beyond the uncertainty and disruption that accompany any other radical technological change. They stem in part from the direction AI development has taken: many leading companies are engaged in a single-minded pursuit of artificial general intelligence (AGI). Why
Expression and purification of β2AR in Sf9 cells The β2AR construct PN1 was expressed and purified as previously described39,42. In brief, Sf9 cells were infected with a PN1-containing baculovirus produced using the BestBac method. Cells were then collected and resuspended in chilled lysis buffer containing 10 mM HEPES, pH 7.4, 1 mM EDTA, 1 μM alprenolol and protease inhibitors
RESEARCH HIGHLIGHT 19 August 2026 Female treefrogs select less carefully when hearing a chorus of males. The dating advice of there are ‘plenty more fish in the sea’ is often not helpful — especially, it seems, for frogs. Claire Hemingway at the University of Tennessee in Knoxville and her colleagues studied the mating choices of
People who live to 110 years and older have large populations of a rare type of immune cell that can kill cancer1, finds a study published today in Cell Reports. It is possible that such cells, called killer T cells, might help people to live to extraordinarily long ages by fighting off cancer — although
Data Ice mass variability was quantified using GRACE and GRACE-FO gravimetry data50 spanning 2003–2024. SMB (precipitation minus meltwater runoff, sublimation, evaporation and wind erosion) outputs from RACMO2.4p1 (ref. 51) and MARv3.14 (refs. 52,53) were used to link precipitation variability to observed ice mass changes. Precipitation variability was assessed using several independent datasets, including ERA5 (ref.
David Fajgenbaum discovered how to repurpose a drug to treat his own rare disease and has dedicated much of his career to repurposing drugs. Credit: Noam Galai/Getty Images for Clinton Global Initiative As a child, molecular biologist Francesca Granata had episodes of skin pain so excruciating that she could not bear even a hug from