Mapping microproteins in the brain might help to understand, and treat, Alzheimer’s disease.Credit: Zephyr/SPL More than 1,000 previously overlooked ‘microproteins’ have been found in samples of human brain tissue, providing researchers with the most comprehensive database yet to study these hidden molecules inside the human brain. Dozens of the tiny proteins showed altered expression in
Mice All mouse experiments were performed according to protocols approved by the Institutional Animal Care and Use Committees (IACUC) at Korea Advanced Institute of Science and Technology (KAIST) and the Institute for Basic Science (IBS), adhering strictly to ethical guidelines. B6.Cg-Tg(APPswe, PSEN1dE9)85Dbo/Mmjax (APP/PS1) mice and B6.Cg-Tg(APPSwFlLon, PSEN1*M146L*L286V)6799Vas/Mmjax (5×FAD) mice were produced in our laboratory and
The video opens with a man in his 80s slumped in a hospital bed, his face hollow as he scrunches his eyes. A jump cut advances the scene three days: the man is alert now, words gathering as he identifies his son. Six months later, he is pictured sitting upright, engaged in conversation. His gaze
The heroic pilot who safely abandoned a crashed plane into a New York City river in 2009 has been diagnosed with Alzheimer’s disease. Captain Chesley ‘Sully’ Sullenberger III, 75, shared the update on his personal website, writing that he was recently diagnosed and is in an early stage. “For now, this means I may not
