Bites from a lone star tick (Amblyomma americanum), which live on white-tailed deer, are the main cause of α-gal allergy in the United States.Credit: BackyardProduction/Getty Thomas Platts-Mills develops a rash if he eats red meat. The immunologist is one of thousands of people who are diagnosed each year with tick-induced α-gal allergy — a life-threatening
Bispecific antibodies (orange and yellow, artist’s illustration) grab onto two different proteins rather than the standard one.Credit: Thom Leach/Science Photo Library Cancer-fighting drugs called bispecific antibodies are having a moment. A growing number are making their way into the clinic, and researchers are developing increasingly elaborate molecules with new capabilities. In the past five years,
The Epstein-Barr virus activates specific T cells in the immune system, causing an attack on nerve cells in the brain and spinal cord.Credit: Steve Gschmeissner/Scientific Photo Library For years, a common virus has been implicated in the development of multiple sclerosis, a disease in which the body’s immune system attacks nerve cells in the brain
Credit: Steve Gschmeissner/Science Photo Library A man and a woman with a rare and devastating autoimmune disease have been in remission for more than 15 years after receiving a stem-cell transplant1. The positive results, which were reported in Med, suggest that the experimental treatment warrants a larger clinical trial, say scientists. The two people had
Age-related memory decline could be caused by ageing immune cells.Credit: JasonDoiy/Getty A type of immune cell circulating in the blood contributes to cognitive ageing, and blocking its effects can reverse the changes, suggests a mouse study published in Immunity on 14 May1. T cells have many jobs, chiefly destroying pathogens. But as people age, a