Genetically encoded cortical depletion Emx1-cre (JAX, B6.129S2-Emx1tm1(cre)Krj/J), Esco2fl/fl (JAX, B6N.129S-Esco2tm1.1Ge/J) and C57BL SCID (JAX, B6.Cg-Prkdcscid/SzJ) mice were used to generate the breeding scheme: male Esco2fl/flPrkdcscid/scid × female Emx1-cre+/−Esco2fl/+Prkdcscid/scid. Breeder and offspring cages were supplemented with breeder chow (Envigo Teklad 2919) and DietGel 76A (with plant protein) to help to increase pup survival. Some breeders were more prone to
This side view of a lab mouse brain shows nerve fibers extending from the human graft (colored with green and red fluorescent proteins) through the mouse brain (colored with blue). Scale bar = 1 mm. S. Pașca lab/Stanford University hide caption toggle caption S. Pașca lab/Stanford University Researchers have developed a new way to install
Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. The flash flood destroyed many buildings and left villages covered in mud and debris.Credit: Arun Sankar/AFP via Getty Satellite images taken just days before the high-altitude collapse of rock and ice that caused a catastrophic flash
Studies in mice suggest that psilocybin, one of the psychoactive compounds in magic mushrooms, could prevent the chemotherapy side effect called neuropathy.Credit: Victor de Schwanberg/SPL For many cancer survivors, the triumph of remission is undercut by a debilitating side effect: hands and feet that feel as though they are constantly burning, prickling with needles or
About 1,600 federal employees who work at the General Services Administration have been forced to relocate from their office on F Street in Washington, DC, to the Theodore Roosevelt Federal Building, roughly two blocks away. Workers say the new building, which also houses staff from the Office of Personnel Management has mice, a caved-in bathroom ceiling, and
Bashor, C. J., Hilton, I. B., Bandukwala, H., Smith, D. M. & Veiseh, O. Engineering the next generation of cell-based therapeutics. Nat. Rev. Drug Discov. 21, 655–675 (2022). Article CAS PubMed PubMed Central Google Scholar Zhou, Y. et al. A small and highly sensitive red/far-red optogenetic switch for applications in mammals. Nat. Biotechnol. 40, 262–272
