Archaeological site and samples Bianfu Cave (26° 27′ 43.65′′ N, 100° 09′ 55.45′′ E) is in Heqing County, western Yunnan Province in southwestern China, approximately 2 km south of the Yinhe River, a secondary tributary of the Yangtze River (Fig. 1a). In 2019, the Yunnan Institute of Cultural Relics and Archaeology and other cooperative institutes conducted excavations on this site. The stratigraphy
Data In each country, we have two waves of data: baseline and endline. In Nepal, we conducted a baseline survey with a random 50% of the sample, and in Kenya, we relied on administrative data instead of baseline survey data. The endline surveys took approximately 30 min to administer and included approximately 20 questions. These questions
Distributed computing Most calculations in this study were performed on the Triton and Pegasus computing clusters at the Frost Institute for Data Science and Computing at the University of Miami. An overview of our computational pipeline is shown in Extended Data Fig. 3a, indicating the calculation phases that required distributed computing. Except for TM-alig13, we
Selection and prioritization of extracellular tumour-derived genes Candidate extracellular tumour-derived genes were identified using a stepwise filtering and prioritization strategy integrating single-cell transcriptomic analyses, protein subcellular localization annotations, functional dependency data, domain-based functional annotation and literature-based curation (Extended Data Fig. 1a). Publicly available scRNA-seq datasets from human14 and mouse15 PDAC were independently analysed. Within each
Krause, J. et al. The complete mitochondrial DNA genome of an unknown hominin from southern Siberia. Nature 464, 894–897 (2010). Article ADS CAS PubMed PubMed Central Google Scholar Reich, D. et al. Genetic history of an archaic hominin group from Denisova Cave in Siberia. Nature 468, 1053–1060 (2010). Article ADS CAS PubMed PubMed Central Google
