- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Expression and purification of SC003-mi3 VLP The mi3-VLP (also known as SC003-mi3) was derived from i3-01 (ref. 66) by introducing two mutations that remove surface-exposed cysteines to prevent aggregation and by genetically fusing a SpyCatcher domain to the N-terminus to enable plug-and-play attachment of SpyTagged proteins54. The plasmid pET28a-SpyCatcher003(SC003)-mi3 (gift from Professor Mark Howarth, Cambridge University)
READ MORE- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
Genetically encoded cortical depletion Emx1-cre (JAX, B6.129S2-Emx1tm1(cre)Krj/J), Esco2fl/fl (JAX, B6N.129S-Esco2tm1.1Ge/J) and C57BL SCID (JAX, B6.Cg-Prkdcscid/SzJ) mice were used to generate the breeding scheme: male Esco2fl/flPrkdcscid/scid × female Emx1-cre+/−Esco2fl/+Prkdcscid/scid. Breeder and offspring cages were supplemented with breeder chow (Envigo Teklad 2919) and DietGel 76A (with plant protein) to help to increase pup survival. Some breeders were more prone to
READ MORE- SCIENCE, Science / Health, Science Mission Directorate, scientists, Space, Space Communications & Navigation Program, Space Launch System (SLS), Space Telescope, space-x-ipo, SpaceX
- September 18, 2026
ChEMBL database molecular pairs From the PostgreSQL version of CHEMBL34 (ref. 4) (https://doi.org/10.6019/CHEMBL.database.34), we filtered the database for compounds with activities reported against a single protein, with either Ki, Kd, IC50 or EC50 as the activity type. To be considered a molecular pair, compounds had to have the same assay ID, the same target ID,
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