Biospecimen processing and quality control Before extracting nucleic acids, pathology quality control (QC) was performed on all frozen and FFPE tumours and normal specimens. From frozen tissue, a 30 mg or smaller piece was prepared, or an equivalent amount of scrolls were cut from a FFPE block, with sections stained with haematoxylin and eosin taken from
Neanderthals are known to have had physiological differences from Homo sapiens, including thicker bones and defined brow ridges, as in this model.Credit: Mike Kemp/In Pictures via Getty Two genetic changes in the genomes of Neanderthals contributed to the extinct hominin’s characteristic robust physique — and the differences persist in modern humans. The variants make carriers
Kucewicz, M. T., Worrell, G. A. & Axmacher, N. Direct electrical brain stimulation of human memory: lessons learnt and future perspectives. Brain 146, 2214–2226 (2023). Article PubMed Google Scholar Ezzyat, Y. et al. Closed-loop stimulation of temporal cortex rescues functional networks and improves memory. Nat. Commun. 9, 365 (2018). Article ADS PubMed PubMed Central Google
RESEARCH BRIEFINGS 05 August 2026 A study of more than one million people shows that rare genetic variants that disrupt the FNIP1 gene are associated with a favourable metabolic profile and a roughly 60% lower risk of cardiometabolic disease than the general population. Silencing genes in the FNIP1 pathway in mice induces fat breakdown and
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People with food allergies are advised to avoid the allergen because treatments are limited.Credit: BSIP/UIG Via Getty Six people who were highly allergic to peanuts can tolerate the nut after receiving a faecal transplant, reports a study published on 5 August in Science Translational Medicine. The small trial1 of 15 people is the first evidence