CIGMA We developed CIGMA to unbiasedly quantify cell-type-shared and cell-type-specific eQTLs in scRNA-seq data. CIGMA avoids bias from eQTL detection power by using a linear mixed model, similar to the GREML model of complex trait heritability12. CIGMA models cell-type-specific pseudobulk data, which is computed by averaging across all cells in predefined cell types, one gene
The Malva platform Malva provides a unified interface to search millions of cells by any RNA sequence. Malva integrates five modular components that operate independently but communicate through a central orchestrator (Extended Data Fig. 1b). When a user submits a query via the public RESTful API—a gene symbol, DNA sequence, or natural language request such
Crystal growth Single-crystal CrSb specimens were grown by the chemical vapour transport technique. Stoichiometric amounts of Cr (chunks, 99.995%) and Sb (Shots, 99.9999%) were used as source material. Iodine was added as a transport agent, calculated to have a pressure of 1 bar at growth conditions. The starting materials were sealed under vacuum in a quartz
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The Norwegian MoBa cohort MoBa is a population-based pregnancy cohort study conducted by the Norwegian Institute of Public Health. Participants were recruited from all over Norway from 1999 to 2008. The women consented to participation in 41% of the pregnancies (n = 112,908 recruited pregnancies)43,54. The cohort includes approximately 114,500 children, 95,200 mothers and 75,200 fathers. The
Saunois, M. et al. The global methane budget 2000–2017. Earth Syst. Sci. Data 12, 1561–1623 (2020). Article ADS Google Scholar Ma, S. et al. Satellite constraints on the latitudinal distribution and temperature sensitivity of wetland methane emissions. AGU Adv. 2, e2021AV000408 (2021). Article ADS Google Scholar Kirschke, S. et al. Three decades of global methane
